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AtCor’s SphygmoCor technology has been featured in over 1,400 peer-reviewed publications in medical journals. The following are some of the key publications on our technology and the importance of central blood pressure in cardiovascular risk assessment, diagnosis, treatment and pharmaceutical development.
 

Central Blood Pressure and Arterial Stiffness Studies

Roman MJ, et. al. Central Pressure More Strongly Relates to Vascular Disease and Outcome Than Does Brachial Pressure; The Strong Heart Study. Hypertension. 2007;50:197-203. [Link to Abstract]

Williams B, et. al. Differential Impact of Blood Pressure-Lowering Drugs on Central Aortic Pressure and Clinical Outcomes. Principal results of the Conduit Artery Function Evaluation (CAFE) Study. Circulation. 2006;113:1213-1225. [Link to Abstract]

Jankowski P, et. al. Pulsatile But Not Steady Component of Blood Pressure Predicts Cardiovascular Events in Coronary Patients. Hypertension 2008 Apr;51(4):848-55. [Link to Abstract]

Guerin AP, et. al. Impact of aortic stiffness attenuation on survival of patients in end-stage renal failure. Circulation 2001 February 20;103(7):987-92. [Link to Abstract]

Recent Publications

Heffernan KS, et. al. Racial differences in central blood pressure and vascular funcation in young men. 2008 Dec;295(6):H2380-7. Epub 2008 Oct 10. [Link to Abstract]

Khalil AA, et. al. Pulse wave analysis: a preliminary study of a novel techique for the prediction of pre-eclampsia. 2009 Jan;116(2):268-76; discussion 276-7. [Link to Abstract]

Review Articles

Safar A, et. al. Central blood pressure and hypertension; role in cardiovascular risk assessment. Clin Sci (Lond) 2009 Feb;116(4):273-82. [Link to Abstract]

Papaioannou T. et. al. Non-invasive Methods and Techniques for Central Blood Pressure Estimation: Procedures, Validation, Reproducibility and Limitations. Curr Pharm Des 2009,15(3),245-53. [Link to Abstract]

Mancia, G, et. al. Guidelines for the Management of Arterial Hypertension: The Task Force for the Management of Arterial Hypertension of the European Society of Hypertension (ESH) and of the European Society of Cardiology (ESC). J Hypertens 2007 June;25(6):1105-87. [PubMed Citation]

Laurent S, et. al. Expert consensus document on arterial stiffness: methodological issues and clinical applications. Eur Heart J 2006 November;27(21):2588-605. [Link to Abstract]

Agabiti-Rosei E, et. al. Central Blood Pressure Measurements and Antihypertensive Therapy; A Consensus Document. Hypertension. 2007;50:154-160. [PubMed Citation]

Pharmacology

Boutouyrie P, et. al. Importance of arterial stiffness as cardiovascular risk factor for future development of new type of drugs. Fundam Clin Pharmacol 2008 June;22(3):241-6. [Link to Abstract]

Protogerou A, et. al. The Effect of Antihypertensive Drugs on Central Blood Pressure Beyond Peripheral Blood Pressure. Part II: Evidence for Specific Class-Effects of Antihypertensive Drugs on Pressure Amplification. Curr Pharma Des 2009, 15(3),272-89. [Link to Abstract]

Nichols W, et. al. Actions of Selected Cardiovascular hormones on Arterial Stiffness and Wave Reflections. Curr Pharma Des 2009, 15(3);304-20. [Link to Abstract]

SphygmoCor Technology Validation

Pauca AL, et. al. Prospective Evaluation of a Method for Estimating Ascending Aortic Pressure From the Radial Artery Pressure Waveform. Hypertension.2001;38(4):932-7. [Link to Abstract]

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